Bone. 2016 Mar;84:57-68. doi: 10.1016/j.bone.2015.12.016. Epub 2015 Dec 23. Review.
Given the polygenic nature of skeletal diseases like osteoporosis and osteoarthritis, validating the function of additional miRNA-associated SNPs has the potential to enhance our understanding of the genetic determinants of bone mass and predisposition to selected skeletal diseases.
Autor: Dole NS, Delany AM.