Myostatin deficiency partially rescues the bone phenotype of osteogenesis imperfecta model mice

Osteoporos Int. 2016 Jan;27(1):161-70. doi: 10.1007/s00198-015-3226-7. Epub 2015 Jul 16.

Myostatin deficiency partially improved the reduced femoral bone biomechanical strength of adult +/oim mice by increasing muscle mass with concomitant improvements in bone microarchitecture and physiochemical properties.

Autor: Oestreich AK, Carleton SM, Yao X, Gentry BA, Raw CE, Brown M, Pfeiffer FM, Wang Y, Phillips CL.