Objectively Verified Parental Hip Fracture Is an Independent Risk Factor for Fracture: a Linkage Analysis of 478,792 Parents and 261,705 Offspring

J Bone Miner Res. 2016 Sep;31(9):1753-9. doi: 10.1002/jbmr.2849. Epub 2016 Apr 30.

Parental Hip Fracture (HF) increased the risk for offspring Major Osteoporotic Fracture (MOF) and HF but not when parental HF occurred after age 80 years. This suggests a more nuanced approach for clinicians trying to stratify fracture risk, and illustrates the enormous potential of parent-offspring record linkage for other familial disorders.

Autor: Yang S, Leslie WD, Yan L, Walld R, Roos LL, Morin SN, Majumdar SR, Lix LM.
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