In vitro lifespan and senescent behaviour of human periosteal derived stem cells

Bone. 2016 Jul;88:1-12. doi: 10.1016/j.bone.2016.04.013. Epub 2016 Apr 19.

Overall, our findings suggest the possibility to use early-passage PDPCs for bone regenerative approaches based on the local recruitment of stem cells, whilst the later cell passages could be a suitable in vitro tool to validate scaffolds intended for bone regeneration in elderly subjects.

Autor: Vozzi G, Lucarini G, Dicarlo M, Andreoni C, Salvolini E, Ferretti C, Mattioli-Belmonte M.
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