Linkage and association analyses using families identified a locus affecting an osteoporosis-related trait.

We provide strong and significant evidence from both linkage and association analyses that the SOST gene may affect the strength of the femoral shaft.

Future investigations should study the relationship between bone mass formation and strength properties of the bones.

Autor: Athanasiadis G1, Malouf J, Hernandez-Sosa N, Martin-Fernandez L,…

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